The properties at Gasthuisstraat 4-2 are located in the historic heart of the Gasthuisstraat, near the site of the medieval hostel. The Gasthuisstraat was one of the most important streets in Zaltbommel, connected to the care of the poor and sick that played a central role in medieval urban life. The buildings in this part of the street reflect centuries of urban continuity and form a fine example of the preserved historic urban fabric.